Release of 'Theo One' Brain Health Portal for Individuals

Theoria Technologies Inc. (Headquarters: Chiyoda-ku, Tokyo, Representative Director and CEO: Kohei Sakata, hereinafter referred to as Theoria) is pleased to announce the release of 'Theo One,' a brain health portal site that proposes and supports personalized strategies for visualizing individual brain conditions and reducing risks or maintaining cognitive functions.

Eisai is working to alleviate the concerns of individuals and their families affected by dementia and to solve social issues, not only by developing therapeutic drugs but also by developing digital solutions and collaborating with other industries to build a 'dementia ecosystem.' Theoria, aiming to construct and operate the core platform of this ecosystem, was established in September 2023.

In just over two years since its establishment, Theoria has created more than ten products that support everything from reducing the risk of dementia to cohabitation (care). However, until now, each product has only existed as a 'point.' This time, we have seamlessly connected and integrated scattered information and products, and released 'Theo One,' a brain health portal site that proposes and supports the optimal solutions tailored to each individual, regardless of whether they are from our company or other companies.

'Theo One' will start by providing action plans and support for actions to maintain brain health in a healthy state where no diagnosis of dementia or MCI (mild cognitive impairment) has been received. In the future, we will gradually expand the functions and target range, and create a society where each of us who faces dementia can live this moment as ourselves.

▼ Theo One URL https://theo-one.com/

Background In the era of 1,000 million people with dementia, eliminating the 'maze of information' that hinders measures, and a compass for protecting brain health and living as oneself The number of people with dementia and MCI (mild cognitive impairment) exceeds 1,000 million (Note 1), and it is estimated that economic losses due to long-term care leave will reach 5.5 trillion yen by 2025 (Note 2), etc., making dementia an urgent issue that the entire society must face.

However, although dementia is the 'disease I do not want to get No. 1,' only about 18% of people are actually taking measures (Note 3). Behind this large gap is a lack of 'information' to correctly understand and properly confront dementia. In the case of Alzheimer's disease, brain changes begin about 20 years before onset, but for many people, the perception is that it 'suddenly happens when you get old,' and it does not lead to specific actions such as 'what should I do now.'

Theoria has developed 'Theo One' to eliminate this maze of information and serve as a compass for everyone to protect their brain health and live as themselves without getting lost.

(Note 1) Cabinet Office 'Heisei 7th Edition White Paper on Aging Society' (Note 2) METI Website 'Long-term Care Measures,' economic impact related to working family caregivers, economic loss of 9.1792 trillion yen multiplied by the ratio of dementia 60% Regarding the ratio of dementia 60%: MHLW Social Security Council Long-term Care Insurance Subcommittee Heisei 22nd Year Progress of Dementia Measures P1 'Current Status and Issues' (Note 3) Taiyo Life Minority and Aging Society Research Institute 'Survey on Dementia' released on September 17, 2025

Overview of 'Theo One' For all users, propose and support your own way of maintaining brain health and life. 'Theo One' is a brain health portal site that proposes and supports the way to maintain brain health and life for all users. In addition to 'preparation for dementia,' we aim to reduce future risks through daily experiences that blend into daily life, such as 'daily fulfillment and brain aging care.' In addition, 'Theo One' is not just a data recording tool. Using data and AI, we will propose the following functions as a brain health partner that draws out users' willingness to take action.

[Main Features] 1. Visualization of 'Brain Condition' through Data Linkage Through the linkage of digital data such as the results of brain analysis AI service 'MVision health' (M Corporation, partially linked with some medical institutions, and planned to expand in the future), brain health degree check tool 'nouKNOW®,' and digital cognitive function check tool 'Espresso,' and in the future, linkage with My Number Portal and daily life data, we will grasp the brain health status of users. We will manage scattered health information in an integrated manner. 2. Personalized Proposal of Lifestyle Habits Tied to 'Purpose in Life' Each user has strong motivations (purpose in life) such as 'I want to continue traveling at least twice a year' and 'I want to attend my grandchild's coming-of-age ceremony in a lively manner.' By proposing actions that are on the extension line of the user's hobbies and lifestyle to protect this purpose in life, we will propose an action plan without forcing it. 3. Companion Support by 'AI Buddy' to Prevent Three-Day Old (Planned to be provided this autumn) The AI buddy will grasp the user's action status. Even when it seems to be buried in the busyness of daily life, it will present a recovery plan without forcing it, etc., and continue to support the continuation of actions. Since the continuation of actions is something that many people feel difficult, we will continue to strengthen the action support function of the AI buddy. 4. Future Simulation of 'Brain Health and Assets' (Planned to be provided next year) Simulate how the current brain health status affects future living independence and asset management. We will support specific 'preparation' to protect your own lifestyle and assets.

Comments from Representative Director and CEO Kohei Sakata Since the company's establishment in September 2023, our vision has been consistent. That is, to connect 'prevention,' 'diagnosis and treatment,' and 'care,' which are divided into information and products regarding dementia, into one line, and to construct a platform where everyone can protect their own brain without getting lost. This time, we have taken a big first step.

What we value most in 'Theo One' is not to impose 'what is generally considered correct.' Just as there are people who know the method of dieting but do not succeed, people do not move with common sense alone. In Theo One, by approaching each person's hobbies and action patterns and presenting options that the person thinks 'I can do this,' we will support continuous efforts without forcing them.

In addition, the solutions we provide are not limited to in-house development. We would like to actively collaborate with partner companies that have excellent technology and provide a variety of options, including products from other companies, on this platform.

By continuously utilizing this platform, we will connect to living a fulfilling life in the 100-year life era in a way that suits you. Through co-creation that transcends all barriers, we will design a society where everyone can maintain their brain health positively.

Future Prospects We will evolve 'Theo One' into the 'brain health infrastructure' that supports the 100-year life era. ・Construction of Companion-type UI/UX that Supports Execution We will implement a mechanism that immediately returns praise and feedback for execution, not just presenting 'what should be done.' We will create an experience where everything is completed within the portal and lower the hurdle for users' 'continuation' to the extreme. ・Expansion of Open Ecosystem Beyond the framework of in-house development