Announcement: Standard ProMax Upgrade to 23 Microdeletion/Duplication Disorders

【Background & Features】 With rising interest in NIPT (Non-Invasive Prenatal Testing), Hiro Clinic NIPT continues to provide high-precision testing and comprehensive support to help expectant parents welcome their babies with peace of mind. Out of the 23 disorders now covered by the expanded testing, 14 are designated as "Intractable Diseases" by the Ministry of Health, Labour and Welfare. Almost all other covered conditions are also recognized as important diseases that may fall under the scope of "Specified Pediatric Chronic Diseases."

In response to requests from expectant mothers and families who want to be informed about a wider range of health risks in advance, we are offering this special opportunity to receive more detailed testing at no additional cost.

【Overview】 ■ Eligible Plan: Standard ProMax Plan ■ Campaign Details: Free upgrade of microdeletion/duplication disorder screening from 7 to 23 items (including MHLW-designated intractable diseases). There are no additional costs for this upgrade. ■ Price: 270,000 yen (297,000 yen including tax). Provided at the usual price. ■ Eligible Testing Period: May 21, 2026 (Thursday) – May 31, 2026 (Sunday). Please note that the campaign period may be extended or terminated without prior notice. ■ Eligible Applicants: Anyone who takes the test during the above period. This applies to testing at all Hiro Clinic locations as well as affiliated clinics nationwide. ■ Booking & Testing Notes: - Plans can be decided after consulting with attending physicians and staff. - This campaign is automatically applied when the "Standard ProMax" plan is selected during the eligible period.

【Main Added Disorders (Partial list of 23)】 - 1p36 deletion syndrome (designated intractable disease) - 4p16.3 deletion syndrome / Wolf-Hirschhorn syndrome (designated intractable disease) - 5p deletion syndrome / Cri-du-chat syndrome (designated intractable disease) - 22q11.2 deletion syndrome / DiGeorge syndrome (designated intractable disease) - Prader-Willi syndrome, Angelman syndrome

About Hiro Clinic With over 75,000 NIPT tests performed, Hiro Clinic delivers results in approximately 2 to 5 days. The reporting rate for Hiro Clinic's NIPT is 99.98%. Hiro Clinic operates in major Japanese cities, employing a network of specialists—including obstetricians, clinical geneticists, pediatricians, and psychiatrists—to collaborate on clinical care.