4133 YanoPha Announces Appointment of Chief Sustainability Officer

Release Date: August 14, 115 Statement Date: August 13, 115 Statement Time: 15:33:23 Company Code: 4133 Company Name: YanoPha Subject: Announcement of Board Approval for the Establishment of Chief Sustainability Officer Applicable Clause: Clause 8 Factual Date: August 13, 115

Details: 1. Type of Personnel Change (Please specify: Spokesperson, Acting Spokesperson, Key Operating Executive (e.g., CEO, COO, CMO, CSO), Financial Officer, Accounting Officer, Corporate Governance Officer, Chief Information Security Officer, R&D Officer, Internal Audit Officer, Litigation/Non-litigation Agent): Chief Sustainability Officer 2. Date of Change: August 13, 115 3. Former Officer’s Name, Title, and Resume: Not Applicable 4. New Officer’s Name, Title, and Resume: Irene Dong / Special Assistant to the Chairman, YanoPha Biotech Co., Ltd. 5. Nature of Change (Please enter 'Resignation', 'Job Adjustment', 'Layoff', 'Retirement', 'Death', 'New Appointment', or 'Dismissal'): New Appointment 6. Reason for Change: New Appointment 7. Effective Date: August 13, 115 8. Other Matters to be Disclosed: None