[Polaris Group] Announcement on the Change of Director at Subsidiary Lumosa Therapeutics

1. Date of change: 2026/05/25 2. Personnel category: Natural person director 3. Former title and name: Chen Hong-wen, Director of Lumosa Therapeutics 4. Former resume: Director of Lumosa Therapeutics 5. New title and name: Hou Yu-hsiang, Director of Lumosa Therapeutics 6. New resume: HR Director of Lumosa Therapeutics 7. Circumstances of change: Resignation 8. Reason for change: Reassignment by the parent company 9. Number of shares held at the time of appointment: Not applicable 10. Former term: Not applicable 11. Effective date of new appointment: Not applicable 12. Change ratio of directors for the same term: Not applicable 13. Change ratio of independent directors for the same term: Not applicable 14. Change ratio of supervisors for the same term: Not applicable 15. Whether more than one-third of directors have changed: No 16. Other notes: The event does not qualify as a matter with significant impact on shareholder rights or securities prices under Article 7, Paragraph 6 of the Enforcement Rules of the Securities and Exchange Act.