【Tokushima City, Tokushima Prefecture】Metallo Balance Test, Which Assesses Cancer and Cognitive (MCI: Mild Cognitive Impairment) Risks with Just 6mL of Blood, Now Accepting Reservations at Tokushima Heisei Hospital Starting August

Renatech Inc. (Headquarters: Isehara City, Kanagawa Prefecture), a company that develops health indicators based on trace elements and applies them to real-world use, announces the opening of reservations for its self-developed and provided screening test, the 'Metallo Balance Test,' which assesses risks of cancer and MCI (Mild Cognitive Impairment), at its partner medical institution, Tokushima Heisei Hospital (Tokushima City, Tokushima Prefecture), for the period from August to October 2026.

With the establishment of a continuous testing system at this hospital, access to the 'Metallo Balance Test' in the Tokushima City area will be stably secured, contributing as a practical option for local residents' daily health management and pre-disease prevention.

Renatech will continue to work with partner medical institutions nationwide to maintain and expand testing availability, aiming to encourage more people to take interest in their health and reflect on their daily health management and lifestyle habits as part of pre-disease prevention.

What is the Metallo Balance (MB) Test?

The Metallo Balance Test is a risk screening (triage) test that objectively evaluates the risk of cancer and MCI (Mild Cognitive Impairment) at the time of blood draw by analyzing the concentration balance of 17 trace elements (metal elements) in the blood.

### Key Features of the Test

- Only one 6mL blood draw: Blood is safely collected under the proper management of medical institutions. The test takes approximately 15 minutes, minimizing physical burden and ensuring safety.

- Site-specific 'Cancer Risk Test': With a single blood draw, cancer risks are evaluated by site (6 sites for men, 9 for women) and scored on a four-tier scale from A to D. - [Men] Lung cancer, stomach cancer, liver cancer, pancreatic cancer, colorectal cancer, prostate cancer - [Women] Lung cancer, stomach cancer, liver cancer, pancreatic cancer, colorectal cancer, breast cancer, cervical cancer, endometrial cancer, ovarian cancer

- Comprehensive 'Cognitive Risk Test (MCI Risk Assessment)': Evaluates all types of cognitive impairment, including not only Alzheimer's type but also vascular and Lewy body types.

- Proven research results and international recognition: Developed through joint research with Kanagawa Prefectural Cancer Center and Chiba Prefectural Cancer Center, supported by a research grant from METI's Go-Tech program. Patented in 9 countries including Japan, with over 100,000 test takers cumulatively (as of March 2026, from April 2019).

Testing Process and Key Pre-Test Notes

- Due to the need for document mailing procedures, advance registration is required by approximately three weeks before the desired test date (fully reservation-based).

- Application: Apply via website or phone. A complete set of test documents will be delivered to your home about one week before the appointment.

- Test Day (Blood Draw): As the test is fully reservation-based, blood draw proceeds smoothly (takes about 15 minutes). Payment is on a post-pay basis, so no on-site payment is required.

- Results Notification: The invoice (payment slip) will be mailed to your home approximately three weeks after blood draw, and test results approximately five weeks after.

### Key Pre-Test Notes

- Food and alcohol: No food after 9 PM the previous day. No alcohol from the previous day. - Hydration: Drink plenty of water to make blood draw easier. - Medications and supplements: Over-the-counter drugs and supplements should not be taken from the previous day. Prescription medications should be taken as usual.

Test Fees (Private-Pay Medical Service)

This test is a private-pay medical service not covered by health insurance. Choose from the following plans based on your needs:

- Cancer Risk Test: ¥19,800 (tax included) - Cognitive Risk Test: ¥19,800 (tax included) - Combined Cancer and Cognitive Risk Test: ¥24,200 (tax included)

- *Listed prices are standard prices. - *Payment will be via 'DSK Post-Pay,' delivered to your home after blood draw. - *Some medical institutions may not offer one of the tests.

Eligibility and Important Notes for the Metallo Balance Test

### Age Eligibility

- Cancer Risk Test: Japanese nationals aged 20 to 80 - Cognitive Risk Test: Japanese nationals aged 50 to 80

- *As this test is developed based on data from Japanese individuals within the above age ranges, those outside these age ranges or non-Japanese nationals may still take the test, but results will be considered 'reference values' only. Please understand this in advance.

### Individuals Who Cannot Take the Test

- Pregnant individuals or those within 6 months postpartum - Individuals currently undergoing cancer treatment or within one year of completing cancer treatment - Individuals undergoing dialysis - Individuals with fractures, blood disorders, or immunodeficiency (excluding lipid abnormalities such as high triglycerides) - Individuals in poor physical condition (e.g., lack of sleep, after an all-nighter, immediately after intense exercise, under severe stress, or with symptoms such as cold, asthma, shingles, allergic rash, or rhinitis)

Overview of Partner Medical Institution

- Test Schedule: Generally Monday to Friday (excluding holidays and clinic closure days) - Medical Institution: Tokushima Heisei Hospital Health Checkup Center - Address: 3-19-2 Iga-cho, Tokushima City, Tokushima 770-0926 🅿️ Parking available 📍MAP - Access: About 5 minutes by car from Tokushima Station / By bus: From Tokushima Station, take the 'Hokka-Ōki Line' or 'Daido 2-chome' bus stop, then 5 minutes walk - Available Tests: Cancer Risk Test, Cognitive Risk Test

- ▼ Check Available Dates and Make a Reservation Here - Schedules for August to October, as well as the latest schedule from November onward, can be viewed and booked anytime via the web reservation system below.

- Metallo Balance Test Web Reservation: https://metallo-balance.net/entry/

### Steps to Check Test Dates and Apply

- Select 'General Public' (red button) on the URL above - Select the corresponding region (Chugoku-Shikoku > Tokushima Prefecture) under 'Find Test Site' - Select 'Tokushima Heisei Hospital Health Checkup Center' as the test site to view currently available specific test dates. - *Each testing slot has a capacity limit. Registration closes once capacity is reached, so please understand in advance.

### ⚠️ Important Request Regarding Testing (Please Read Carefully)

- Please refrain from contacting the medical institution directly: The hospital front desk or phone line cannot handle any inquiries or applications for this test. All inquiries and applications regarding the test must be directed to Renatech.

- For more details and applications:

- Metallo Balance Test Information Site (for detailed test info): https://www.mbkensa.com/

- Toll-Free Hotline: 0120-785-602 (Renatech: Weekdays 9:00–17:00)

- ▼ Digital Version of Metallo Balance Test Brochure

- d182526-32-0e4f62718d32012f045d4f2c064af23b.pdf

- 🏥 Partner medical institutions nationwide are also being recruited! For information on introducing the Metallo Balance Test, click here.

- Metallo-Balance Original Character: Metalona-chan

Renatech Inc. is an innovative company developing proprietary technologies in the medical and health fields, aiming to assess early risks of diseases such as cancer, as well as in environmental fields. The company has been selected for the '300 Outstanding SMEs and Small-Scale Enterprises' program by METI and the Small and Medium Enterprise Agency, recognizing its high technological capabilities and social contributions.