Kushiro, Hokkaido: 'Metallo Balance Test' for Cancer and MCI Risk Assessment with Just 6mL Blood Draw Now Accepting Reservations at Kushiro Kouninkai Rehabilitation Hospital Starting September

Renatech Inc. (headquartered in Isehara, Kanagawa Prefecture), a company that develops health indicators based on trace elements and applies them to real-world use, announces the opening of reservations for its proprietary screening test, the 'Metallo Balance Test,' which evaluates risks for cancer and MCI (mild cognitive impairment). The test will be available at its partner medical institution, Kushiro Kouninkai Rehabilitation Hospital (Kushiro City, Hokkaido), with reservation slots opening for Saturday, September 5, 2026, and Saturday, October 3, 2026.

With the establishment of a continuous testing system at this hospital, access to the 'Metallo Balance Test' in the Kushiro City area of Hokkaido will be stabilized, contributing as a local option for personal health management and pre-disease care.

Renatech will continue to maintain and expand testing availability nationwide in collaboration with partner medical institutions, aiming to encourage more people to take interest in their health and use the test as a trigger to review daily health habits and lifestyle for preventive care.

What is the Metallo Balance (MB) Test?

The Metallo Balance Test is a risk screening (triage) test that objectively assesses the risk of cancer and MCI (mild cognitive impairment) at the time of blood draw by analyzing the concentration balance of 17 trace elements (metal elements) in the blood.

### Key Features of the Test

- Only one 6mL blood draw: Blood is safely collected under the proper management of medical institutions. The test takes approximately 15 minutes, minimizing physical burden and ensuring safety.

- Organ-specific 'Cancer Risk Test': With a single blood draw, cancer risks are evaluated by body part (6 sites for men, 9 sites for women) and scored on a four-tier scale from A to D. - [Men] Lung cancer, stomach cancer, liver cancer, pancreatic cancer, colorectal cancer, prostate cancer - [Women] Lung cancer, stomach cancer, liver cancer, pancreatic cancer, colorectal cancer, breast cancer, cervical cancer, endometrial cancer, ovarian cancer

- Comprehensive 'Cognitive Risk Test (MCI Risk Assessment)': Evaluates all types of cognitive impairment, including not only Alzheimer’s type but also vascular and Lewy body types.

- Proven research track record and international recognition: Developed through joint research with Kanagawa Cancer Center and Chiba Cancer Center, supported by a research grant from the Ministry of Economy, Trade and Industry’s Go-Tech program. Patented in 9 countries including Japan, with over 100,000 test-takers cumulatively (from April 2019 to March 2026).

Testing Procedure and Key Pre-Test Instructions

* Due to the need for document mailing procedures, advance registration is required approximately three weeks before the desired test date (fully reservation-based system).

- Registration: Apply via the website or by phone. A complete set of test documents will be delivered to your home approximately one week before your scheduled appointment.

- Test Day (Blood Draw): As the system is fully reservation-based, blood draws are conducted smoothly (taking about 15 minutes). Payment is made after the test, so no on-site payment is required.

- Results Notification: Your invoice (payment slip) will be mailed to your home approximately three weeks after blood draw, and your test results will follow approximately five weeks after.

### Key Pre-Test Instructions

- Food and Alcohol: No food after 9 PM the previous day. No alcohol consumption the day before. - Hydration: Drink plenty of water to facilitate blood draw. - Medications and Supplements: Over-the-counter medicines and supplements should not be taken the day before. Prescription medications should be taken as usual.

Test Fees (Private-Pay Healthcare)

This test is a private-pay service not covered by health insurance. Choose from the following plans based on your needs:

- Cancer Risk Test: 19,800 JPY (tax included) - Cognitive Risk Test: 19,800 JPY (tax included) - Cancer and Cognitive Risk Test (Combo): 24,200 JPY (tax included)

* Listed prices are standard rates. * Payment will be via 'DSK Postpay,' delivered to your home after blood draw. * Some medical institutions may not offer one of the tests.

Eligibility and Important Notes

### Age Eligibility

- Cancer Risk Test: Japanese nationals aged 20 to 80 - Cognitive Risk Test: Japanese nationals aged 50 to 80

* As this test is developed based on data from Japanese individuals within the specified age range, individuals outside this range or non-Japanese nationals may still take the test, but results will be considered 'reference values' only. Please understand this in advance.

### Individuals Who Cannot Take the Test

- Pregnant individuals or those within 6 months postpartum - Individuals currently undergoing cancer treatment or within 1 year of completing treatment - Individuals undergoing dialysis - Individuals with fractures, blood disorders, or immunodeficiency (excluding lipid disorders such as high triglycerides) - Individuals feeling unwell (due to lack of sleep, after an all-nighter, immediately after intense exercise, under severe stress, or with symptoms such as cold, asthma, shingles, or allergic rash/rhinitis)

Overview of Partner Medical Institution

- Test Schedule: First Saturday of each month (excluding holidays and clinic closures) - Medical Institution: Kushiro Kouninkai Rehabilitation Hospital - Address: 3-9-13 Hoshigaura-dori, Kushiro City, Hokkaido 070-0030 (former Hoshigaoka Hospital) 🅿️ Parking available 📍 MAP - Access: 5 minutes by car from JR Shintakamori Station - Available Tests: Cancer Risk Test and Cognitive Risk Test

▼ Check Available Dates and Make a Reservation

The test schedules for September and October, as well as the latest schedule from November onward, can be viewed and booked anytime via the web reservation system below.

Metallo Balance Test Web Reservation: https://metallo-balance.net/entry/

### Steps to Check Dates and Apply

- Select 'General Public' (red button) on the URL above - Select the relevant region (Hokkaido) under 'Find a Test Site' - Select 'Kushiro Kouninkai Rehabilitation Hospital' as the test site to view currently available specific test dates. * Each testing slot has a capacity limit. Registration closes once full, so please understand in advance.

⚠️ Important Request Regarding Testing (Please Read Carefully) Please refrain from contacting the medical institution directly: The hospital front desk or phone line cannot handle inquiries or reservations for this test. All questions and reservations regarding the test should be directed to Renatech.

For more details and to apply:

Metallo Balance Test Information Site (for full test details): https://www.mbkensa.com/

Toll-Free Hotline: 0120-785-602 (Renatech: Weekdays 9:00–17:00)

▼ Digital Version of the Metallo Balance Test Brochure

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🏥 Partner medical institutions nationwide are also being recruited! For information on introducing the Metallo Balance Test, visit:

Metallo Balance Original Character: Metalona-chan

Renatech Inc. is an innovation company developing proprietary technologies in the medical and health fields—aiming for early risk assessment of diseases such as cancer—as well as in environmental fields. The company has been selected as one of the '300 Outstanding SMEs and Small-Scale Enterprises' by the Ministry of Economy, Trade and Industry and the Small and Medium Enterprise Agency, recognizing its advanced technological capabilities and social contributions.