Bible of Anti-Aging Unveiled, Exploring Cutting-Edge Aesthetic Medicine and Self-Care: "Beauty Regenerates" Released

Medical Care Service Co., Ltd. (Saitama, Saitama City / President: Norio Yamamoto), a group company of Gakken Holdings Co., Ltd. (Tokyo, Shinagawa / President & CEO: Hiroaki Miyahara), released "Beauty Regenerates - A Textbook of Aesthetic Medicine and Self-Care for Adults" on July 2, 2026 (Thu).

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In 2026, the common understanding of beauty will be overturned. A textbook for a "new way of living" beyond anti-aging.

This book is for women in their 40s and 50s who are starting to feel that their regular skincare is not enough. Moving beyond the conventional framework of anti-aging, which focuses on "hiding blemishes and wrinkles, and adding what has been lost," it presents a roadmap for well-aging from the perspectives of "rejuvenation medicine" and "longevity medicine."

Dr. Hiroshi Nomura, director of N2 Clinic and author of the book, states that true "beauty" is never created solely on the surface of the skin (external appearance). Sustainable "beauty" is achieved only by incorporating "internal body care," such as aesthetic drips and regenerative medicine, along with lifestyle habits like diet, sleep, and exercise.

"Adults" need care for their "foundation" as well as their "appearance."

The New Concept of Rejuvenation: Rebooting Mind and Body at the Cellular Level

Women in their 40s and 50s today possess extremely high beauty literacy.

However, information of unknown origin flooding the internet, or unscientific approaches that simply claim to be "gentle on the skin," cannot combat the structural changes in the skin (aging of the foundation) that occur with age.

Until now, aging care has primarily been "reactive beauty (anti-aging)" that addresses problems after they occur, such as using lasers to remove blemishes and filling wrinkles with hyaluronic acid. However, the premise of this approach is changing significantly.

・Realization of the limitations of "temporary treatments."

Among women with a high sensitivity to beauty, there is a growing realization of the limitations: "Simply applying expensive creams from the outside cannot stop the decline of the skin's foundation (cellular factory)," and "Treatments that continuously force-fill wrinkles can lead to an unnatural and unsightly appearance (overdone look)." This is why the demand for "fundamental regeneration" that awakens the cells themselves is rapidly increasing.

・The advent of the "100-year lifespan era" and increased awareness of well-aging.

People's interest is shifting not just to the extension of average lifespan, but to "how to age gracefully and healthily (well-aging)." The demand is for the essential value of "maintaining physical and mental performance" to live a full 100 years, rather than merely trying to look younger superficially.

・Dramatic advancements in aging treatment attracting attention from the global scientific and investment communities.

Research aimed at "controlling and reversing aging itself," once a distant dream, is now rapidly developing into actual medical treatments. Investors and scientists worldwide are pouring enormous funds into this field.

The real desires of the adult generation, who feel the limitations of "temporary beauty," combined with the dramatic advancements in "cutting-edge science that controls aging," are leading to the demand for "rejuvenation medicine" and "longevity medicine" as a smart new norm for adults, going beyond anti-aging.

While reviewing well-known existing treatments, this book allows readers to update their choices for the adult generation.

【In-depth Trend Analysis】 Latest Keywords to Change Your Skin's Destiny from Your 40s Onward

・From "applying collagen" to "generating collagen from within."

The fundamental reason why skin conditions are difficult to recover from after the age of 40 is not just moisture deficiency, but the decline and decrease in the function of "cellular factories (fibroblasts)" that produce collagen and other substances. This section logically explains the true value behind the ingredient lists of high-end cosmetics.

・Graduating from "unnatural youthfulness." "Skin regenerative medicine" for a naturally elegant appearance.

Instead of unnaturally filling wrinkles with hyaluronic acid, the reality of next-generation aesthetic medicine involves nurturing cells themselves using components of one's own blood. This delves into the secrets of "beauty that protects" from the foundation, without an "overdone" look.

・The core of the trend: "Exosomes" and the anti-aging protein "Klotho."

This section explains "exosomes" and "stem cells," which are becoming must-haves among those with high beauty awareness. Furthermore, it covers the latest developments in rejuvenation research that the world is watching, including the shocking "KLOSOME®," a new preparation related to the anti-aging protein "Klotho," comprehensively covering global medical trends.

"Stem cell therapy," which has become frequently heard of recently, has a high potential to change the future of aesthetic medicine.

A Doctor from Tokyo University's Department of Plastic Surgery, at the Forefront of Regenerative Medicine, Thoroughly Explains Anti-Aging Based on Scientific Evidence.

Many media outlets targeting women, such as social media, the internet, and women's magazines, feature "aging care" and attract attention.

However, what readers truly seek is not information of unknown origin from the internet, but reliable "scientific evidence."

This book, authored by Dr. Hiroshi Nomura, director of N2 Clinic, a rising doctor who continues cell research after graduating from Tokyo University's Department of Plastic Surgery and studying abroad in the US, imparts the "correct discernment (literacy)" to avoid being swayed by the flood of beauty information.

【Author】

Hiroshi Nomura (Director, N2 Clinic Hotel Chinzanso Tokyo Branch, General Incorporated Association Katsumi-kai)

After graduating from the University of Tokyo School of Medicine, he joined the Department of Plastic Surgery at the University of Tokyo with the aim of clinical application of regenerative medicine. After engaging in research and clinical practice of breast reconstruction and adipose tissue-derived stem cells, he studied abroad in the US for basic research in regenerative medicine. Upon returning to Japan, he has promoted the clinical application of stem cell culture supernatant and aesthetic regenerative medicine. Currently, he is working on integrated medical care for beauty, health, and longevity, with the theme of "personalized optimization of regenerative medicine." He is also a private researcher at the Department of Community and Geriatric Medicine, Graduate School of Medicine, Kyoto University, and a special medical advisor to the Gakken Dementia Prevention Research Lab. He lectures and conducts research on regenerative medicine both domestically and internationally.

【Table of Contents】 (Excerpts)

Chapter 1: Adult Skin Cannot Be Addressed with Previous Beauty Approaches

It is natural for blemishes, wrinkles, and sagging to become noticeable. Five factors that accelerate changes in skin structure and aging.

Chapter 2: The Basis of Anti-Aging - Daily Self-Care

Focus on "moisturizing power" and "functional ingredients" in cosmetics. Start using supplements after checking what is lacking.

Chapter 3: Aesthetic Medicine for Truly Beautiful Appearance - Skin

There is "curative beauty" and "protective beauty" in aesthetic medicine. How to conduct consultations without failure and find a reliable doctor.

Chapter 4: Achieving Your Ideal Body Shape - Aesthetic Medicine for the Body

Understand the treatment options that adults should consider, such as liposuction and diet drips.

Chapter 5: Aging Healthily - Aesthetic Medicine for the Inside of the Body

Stem cell therapy, PRP therapy. How to incorporate suitable aesthetic drips (NMN drip, high-concentration vitamin C drip, etc.).

Special Chapter: The Forefront of Rejuvenation Treatments that Prevent Aging and Regenerate Skin: "KLOSOME®"

Product Overview

Product Name: "Beauty Regenerates - A Textbook of Aesthetic Medicine and Self-Care for Adults"

Author: Hiroshi Nomura (Director, N2 Clinic Hotel Chinzanso Tokyo Branch, General Incorporated Association Katsumi-kai)

Price: 2,530 yen (tax included)

Release Date: July 2, 2026 (Thu)

Format: A5 size / 160 pages

E-book: Available

ISBN Code: 978-4-05-802754-7

Published by: Medical Care Service Co., Ltd.

Published and Distributed by: Gakken Co., Ltd.

Gakken Publishing Site: https://hon.gakken.jp/book/2080275400

【Click Here to Purchase This Book】

Amazon https://amzn.asia/d/0j34biem

Rakuten Books https://books.rakuten.co.jp/rb/18591513/

Kinokuniya Shoten https://www.kinokuniya.co.jp/f/dsg-01-9784058027547

About Medical Care Service Co., Ltd.'s Publishing Business

Since November 2022, our company has been publishing books for home caregivers, care workers, students, and those engaged in health promotion and prevention of dementia and diseases. Within the Gakken Group, which has published medical and nursing books, and health and home medical books, we will continue to publish high-quality content by leveraging the knowledge cultivated through our care business, which has focused on dementia care.

●Inquiries Regarding This Matter●

Medical Care Service Co., Ltd.

29F, Land Axis Tower, 11-2 Shintoshin, Chuo-ku, Saitama City, Saitama Prefecture 330-6029

Please use the inquiry form on the right: https://www.mcsg.co.jp/contact/

*Please include "Beauty Regenerates." in the subject line.

Medical Care Service Co., Ltd.

Founded in Saitama City, Saitama Prefecture in 1999. Specializing in dementia care since its founding, the company operates a diverse range of care services, primarily through its group homes "Ai no Ie," and assisted living facilities "Ensemble" and "Famille New." Currently, it operates over 380 care facilities nationwide. Leveraging its long-cultivated expertise, the company is expanding its business beyond care services. In February 2026, it strengthened its home support services by opening the visiting nursing station "Ai no Ie Mirai." It is also addressing social issues through multifaceted approaches, including consulting for care providers, wellness services, and overseas expansion, primarily in China. With the brand message "Beyond Dementia," the company aims to realize a society where everyone, including those with dementia, can live as they are, naturally.

https://www.mcsg.co.jp/ Established: November 24, 1999 Location: 29F, Land Axis Tower, 11-2 Shintoshin, Chuo-ku, Saitama City, Saitama Prefecture 330-6029 Representative: President & CEO Norio Yamamoto Employees: Approximately 7,500 (as of September 2025) Sales: 42.5 billion yen (as of September 2025) Locations: 381 facilities in 33 prefectures in Japan (as of July 1, 2026); 16 facilities overseas (China) (as of March 31, 2026)

Gakken Holdings Co., Ltd.

https://www.gakken.co.jp/ ・President & CEO: Hiroaki Miyahara ・Date of Incorporation: March 31, 1947 ・Capital: 19,817 million yen ・Sales: 199.1 billion yen, Consolidated Subsidiaries: 82 companies (as of September 2025) Listed on the Tokyo Stock Exchange Prime Market (Securities Code: 9470) ・Address: 2-11-8 Nishi-Gotanda, Shinagawa-ku, Tokyo 141-8510 ・Phone: 03-6431-1001 (Main) ・Business Activities: A holding company engaged in education and medical/welfare-related businesses, founded in 1946. Education Field: Classroom and cram school business, including "Gakken Kyoshitsu"; Publishing and content business, including learning materials; School and nursery business, including textbooks and childcare supplies. Medical Welfare Field: Serviced housing for the elderly; Dementia group home business; Childcare support services, including nursery schools and after-school care. Global: Activities and business development in over 150 countries.