6550 Polaris Pharmaceuticals-KY

Disclosure Date: 1150818 Statement Date: 1150817 Statement Time: 223836 Company Code: 6550 Company Name: Polaris Pharmaceuticals-KY Subject: Announcement on the dissolution of subsidiaries DesignerRx Europe Limited and Polaris Pharmaceuticals Ireland Limited Applicable Clause: Clause 51 Factual Date: 1150817

Details: 1. Factual Date: 115/08/17 2. Company Name: Subsidiaries: DesignerRx Europe Limited and Polaris Pharmaceuticals Ireland Limited 3. Relationship with Company (please enter Parent or Subsidiary): Subsidiary 4. Cross-shareholding Ratio: 100% 5. Reason for Occurrence: As the aforementioned subsidiaries currently have no actual operational needs, and based on overall group operational and organizational planning, the company intends to proceed with dissolution and deregistration procedures in accordance with local relevant laws and regulations. 6. Response Measures: After board approval, the company will proceed with dissolution and deregistration procedures in accordance with the relevant laws and regulations of each subsidiary's jurisdiction. 7. Other Matters to be Disclosed (if the subject of the event or resolution is a publicly listed company or above, this material information also meets the criteria under Article 7, Paragraph 9 of the Enforcement Rules of the Securities and Exchange Act regarding matters significantly affecting shareholders' rights or securities prices): The aforementioned subsidiaries currently have no actual operations, and this dissolution and deregistration will have no significant impact on the company's financial condition or business operations.